More and more in the news we hear about senseless acts
committed by serial killers and murderers. And we ask ourselves, how can a
human being even think about doing something so evil and harmful to another
human being? We question the intentions of these killers and try to figure out
what is going on inside their heads that could trigger such violent actions. Sadly, most of the time we aren’t able to question their intentions because most of these troubled
individuals end up committing suicide.
During the first couple weeks of Neuroscience Seminar, we had Brian Sweis come in and talk about research centering around the orbitofrontal cortex (OFC). He explains
how humans with damage in this region do not experience regret and how fMRI
tests have shown functional activity in the OFC region during regret. However
in nonhuman primates, specifically rats, we are not sure if they are even
mentally capable of experiencing regret. A decision making task called
Restaurant Row was constructed where the rats were put in a series of take or
skip choices involving food. The data suggested that the OFC is indeed vital
for representing outcomes when animals think about past decisions. In the end,
we know that rats experience regret but we are still not clear if the orbitofrontal
cortex is necessary for the emotion of regret. However, there is evidence that
the orbitofrontal cortex is active and necessary for experiencing regret in
humans and damage to it results in no showing of regret and anticipation of
negative consequences. This led me to question if we can further our research
and perhaps find a connection between brains of serial killers and
orbitofrontal cortex damage. The orbitofrontal cortex, in my opinion, could be
the reason for the creation of serial killers and murderers when damaged.
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Works Cited
Adams, Tim. "How to Spot a
Murderer's Brain." The Guardian.
Guardian News and Media, 11 May 2013. Web. 05 Mar. 2016.
Steiner, Adam P., and A. David Redish.
"Behavioral and Neurophysiological Correlates of Regret in Rat
Decision-making on a Neuroeconomic Task." Nature Neuroscience Nat Neurosci 17.7 (2014): 995-1002. Web.
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