Friday, March 4, 2022

Misaligned feeding impairs memories


Sleep and circadian rhythms are concepts good to understand the importance of how cognitive 

function works. There are many times we often are on the go and don't have the time to eat or even times 

where as society we forget to eat. As we grow fond and older , we often have gotten told that eating 

healthy foods and getting proper rest can help, bodily joint functions, immunity, etc. Often in society we 

never understand how eating during late hours affect you as an individual. In this article the overall 

concept from this article is how the influx of food at different times throughout the day affect sleep in 

which sleep plays a role in our learning and memory. In this article it states that the (SCN) 

suprachiasmatic nucleus is unaltered, however, there are other parts of the brain that effect these 

inconsistent feed times. A study conducted by multiple scientists explained how people were finding it

difficult between sleep and the time to consume food. 


Scientist wanted to know how misaligned feeding times didn't alter the suprachiasmatic, but it does 

impact the hippocampus LTP and CREB Expression. Throughout the experiment there were times in

which the mice in this experiment were restricted to eat. Doing this so they can see the effects of 

cognition of the brain. 


In the experiment, they used male mice putting them on cycles that got them acclimated to their 

environment. Researchers measured each different mouse by putting them in separate cages to 

differentiate the mouse but also manipulate behavior. The researchers found that misaligned mice in the

experiment caught up to the aligned mouse in daily food consumption. 


Works Cited 


Loh, Dawn H, et al. "Misaligned Feeding Impairs Memories." ELife Sciences Publications, Ltd, 10 

Dec. 2015, https://prod--journal.elifesciences.org/articles/09460

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