Wednesday, December 14, 2016

Erasing Bad Memories



Imagine a moment in your life where you got bullied or experienced an embarrassing moment in front of your crush. Everyone’s first instinct is to say “I wish I could get rid of that moment.” With the advancements in technology, that day might not be far when memory modification could become part of everyday life. We see drugs such as Adderall and caffeine being used around us to enhance our cognitive abilities to ace an exam or to exceed at a project. The concept of altering our cognitive abilities and memories isn’t a new topic in the scientific world. There have been numerous amounts of experiments performed thus far to test the effects of specific drugs on our brains whether it’s to find a cure for a disease or to discover the impact on cognition and memory but now the question of modifying memories has become very popular. I had the opportunity to hear Dr. Joseph Vukov from Loyola University Chicago speak about findings on memory modification; he discussed the benefits of memory modification along with the ethical issues that coincide it.



               
   Dr. Joseph Vukov mentioned certain circumstances in which memory modifying technologies would be a good thing. One such example is in soldiers with PTSD. These individuals had no control over the situation they were in and developed a disorder with no fault of their own. Wouldn’t it be a relief to relieve soldiers of the memories that are causing the PTSD? Most individuals would say yes but the problem occurs when considering all the details of applying the memory modification. When would the treatment be provided: before or after coming from war? What would be the specific guidelines for the treatment? Who will determine whether an individual receives memory modification? The topic has been sparked but there are too many questions left to be answered. Hopefully with time, we can figure out the logistics behind the technology.
                 
                  If we altered our memories, wouldn’t that change our personality and our perspective on life? This is another important question that is also raised. A lot of the decisions we make are based on past situations and outcomes. If we got rid of all of our bad memories, then what will be the motivation of our future goals and desires. For example, if you were bullied as a child, you might be part of organization that are anti-bullying. Without the negative experience of being bullied, you might not be part of those organizations or sympathetic towards victims of bullying.

                  We already know that memory isn’t a tape that can be rewinded but rather it can be modified and gaps are filled in as we try to recall something. A study by Susumu Tonegawa from MIT showed that planting false memories in a mice brains was possible. The brain doesn’t distinguish between real and false memories; the neural mechanism for memory didn’t change when a false memory was implanted.

                  Another study performed by Li-Heui Tsai discovered a gene called Tet1 that is important to extinct memory. By enhancing the gene, there might be a possibility to replace terrifying memories with more positive memories of the situation. The experiment tested the effects of this by conditioning mice to fear a specific cage when they were mildly shocked. After the mice formed the association between the cage and being shocked, the mice were put in the cage but weren’t shocked. Later on, the mice with normal Tet1 weren’t afraid of the cage due to the new memories of no shock replacing the old memories of being shocked. Mice lacking Tet1 remained fearful of the cage. The experiment shows that Tet1 plays a role in memory. The results might be useful in soldiers with PTSD because enhancing the Tet1 in these individuals might replace their awful memories with more positive ones. 
 
                  Memory modification technology is an increasing topic which integrates many areas of studies such as Psychology, Philosophy, and Neuroscience. While experiments are being conducted on the scientific aspect of the topic, it’ll be interesting to see how the ethical aspect turns out. Who will determine whether an individual receives treatment? A Physician? A Psychologist? Until these guidelines are formed, we’re left to our imagination and movies.


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