Wednesday, December 12, 2018

Alcohol Debate


Alcohol continues to resurface as a subject of controversy. The health industry undertakes constant debate as to whether alcohol consumption is good or bad for one’s health. Evidence on the positives and negatives of alcohol can be found in magnitude from a variety of sources. As new research on the physical effects of alcohol consumption and its health effects emerge every day, it can be challenging for a growing adult to make the choice to include alcohol in their life. In a world that broadcasts alcohol in movies and shows as a positive, entertaining substance, consumption of alcohol in adolescence has grown. This in turn, can have significant effects on the development of the body.

Jaime Roitman investigated how alcohol consumption during adolescence effects decisions associated with risk. Rats were used as the subjects and were divided into two groups. The experimental group was allowed access to gelatin containing ethanol, allowing the rats to consume the ethanol at their own free will. The control group was allowed access to gelatin lacking ethanol. Based on daily consumption levels, six rats were placed into the high ethanol consumption group and six were placed into the low ethanol consumption group.  Forty days after ethanol exposure terminated, behavioral testing began. Rats were classified as adult animals when behavioral testing was conducted.  The behavioral tests consisted of two levers. When pressed, one lever provided a same size certain reward. In contrast, the other lever provided larger, but uncertain rewards. Prior to the behavioral tests, preference training was conducted to ensure no presence of preference for a specific lever. Four microwires were surgically inserted into the orbitofrontal cortex of each animal to monitor and record neuronal activity. The control and ethanol low group chose the risky lever significantly less in comparison to the ethanol high group. The results of the electrophysiological recordings showed that the animals in the higher ethanol group had reduced levels of activity to rewards in only one of the five populations of neurons. The decrease in response to reward, therefore is contributing to the increase in risky choices. This is just one study that showcases a potentially harmful effect of alcohol consumption during adolescence. Generally speaking, seeing that alcohol has an effect on brain function should caution consumers to be more aware of how great of an effect alcohol can have on the body.

In a recent article, “Is Moderate Drinking Even Moderately Good For Us?” Tamar Haspel spoke on the positives of drinking that are commonly known to society. Haspel presented multiple perspectives as to why drinking has been known to have health benefits. She also states that many of these studies have come under investigation as being flawed. Although moderate drinking has been show to reduce heart disease, cholesterol, and inflammation, negative consequences are still prevalent.

Both pieces showcase the effects moderate drinking can have on the body. It is widely agreed upon that heavy drinking is detrimental. In regards to overall mortality, it is hard to pinpoint how much of an effect alcohol has since individuals who drink and those who do not tend to have very different lifestyles. It was mentioned in Roitman’s research that they were unable to determine why some rats chose to consume more ethanol than others. It was hypothesized that the difference could be correlated to “neurophysiological differences resulting from early life stress” (Roitman 1373). Haspel’s article also tackled a similar question asking why some individuals choose to drink more than others. It is mentioned that it could be in correlation to a gene known as rs1229984 which could control the way you feel after you have consumed alcohol. Those who had the gene may feel the undesirable after effects of drinking such as feeling ill or uncomfortable to a greater extent than those how go not possess the gene. This could be a new way in which researches approach subjects for alcohol testing. 

Although the debate on alcohol and its range of consequences awaits much more research, each new piece of information pushes society one step closely to understanding the complexity of alcohol consumption.


Roitman, Jaime Donahey. “Consequences of Adolescent Ethanol Consumption on Risk
                             Preference and Orbitofrontal Cortex Encoding of Reward.”
                             Neuropsychopharmacology (2016) 41, pg. 1336-1375
 
Haspel, Tamar. “Is Moderate Drinking Even Moderately Good For Us?” National Geographic,  
                             National Geographic, 27 Apr. 2016, www.nationalgeographic.com/people-and-
                             culture/food/the-plate/2016/04/27/is-moderate-drinking-even-moderately-
                             good-for-us/.






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