Monday, December 10, 2018

Autism Spectrum Disorder: How Your Face Can Say it All


Autism spectrum disorder is a common developmental disorder affecting the communication and behavior of a patient. Several symptoms such as being slow to respond or having difficulty with facial expressions are common amongst those who are Autistic. It is important to recognize that because Autism is a spectrum, the patients with Autism have varying symptoms and treatment plans. Although people with Autism can be high functioning and can be an integral part of society, there is still fascinating research being done to find out when Autism develops and the early signs that exist.
            In Pam Belluck’s article “Study of How We Look at Faces May Offer Insight Into Autism,” discusses how strongly genetics may influence how children seek out social experiences and facial expressions. In a study conducted, the researchers identified data and looked at how children look at faces, “ including which features they focus on and when they move their eyes from one place to another." In this study, scientists “tracked the eye movements of 338 toddlers while they watched videos of motherly women  as well as of children playing in a day care center. The toddlers, 18 months to 24 months old, included 250 children who were developing normally (41 pairs of identical twins, 42 pairs of nonidentical twins and 84 children unrelated to each other). There were also 88 children with autism.” They tested the same mechanisms but with mouths and found that they follow a similar pattern. After conducting the research, children with autism ended up spending significantly less time looking at faces and more time looking at objects. Those conducting the studies were able to identify someone with autism just by looking at the eyes; as seeking out social information was the behavior that was driven by the genetics.
            In Dr. Maggie Guy’s research, she observes visual attention in those with autism spectrum disorder with a primary focus on infant siblings of children. Guy observed N290 and P400 levels as components that are strongly associated with  face processing in children. The aim of her study was to examine electrophysiological correlates of specialized face processing in two distinct groups of 12-month-old infants at higher risk for Autism based on familial history. In order to do so, Guy recruited dozens of 12-month-old infants who had no family history of ASD and were shown face and toys upon arrival at the lab. Characters from Sesame Street were used as attractor stimuli. The trial aimed for subjects to respond to familiar and unfamiliar faces. Results from the experiment indicate that infants at increased risk for ASD demonstrate unique patterns to both familiar and novel stimuli. The results show that patterns of attention and face processing within the first year of life suggest syndrome-specific pathways to similar behavior outcomes. In other words, it is clear that genetics played a role in facial recognition and anxiety based behaviors.
            In both the article and the lecture given by Dr. Guy, facial recognition seems to be the key measurable variable for the severity of Autism at an early age. During both experiments, children indicated a sense of anxiety at some point for novel stimuli, which indicates some form of Autism. Both found correlation in attention scores amongst relatives and people who are related. In fact, one thing that was measured was the attention to specific parts of the face, such as the mouth or the eyes. In Guy’s research, the N290 and P400 levels displayed an inverse correlation for novel stimuli versus positive emotion. This was also demonstrated in the twin studies conducted by the researchers in the article.
           



















Works Cited


2. Guy, Maggie and Richards. John and Tonnsen. Bridgette and Roberts, Jane. (2018). Neural correlates of face processing in etiology-distinct 12-month old infants at high-risk of autism spectrum disorder. Developmental Cognitive. 29. 61-71. 10. 1016/ j.dcn.2017.03.002

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