As
we know, adolescence is a critical period during human development as it
represents an individual’s mental and physiological transition from childhood
into adulthood. Unfortunately, the vast amount of growth and development that
characterizes this phase of life is often hindered by excessive drug and
alcohol abuse that is heavily idealized and marketed in today’s society,
especially to youth. According to a 2011 study conducted by the Centers for
Disease Control and Prevention (CDC), 21.91% of high school students surveyed
admitted to having had five or more drinks of alcohol in a two-hour period—which
is often the amount used in identifying alcoholism—within 30 days of taking the
survey. Despite this prevalence of alcohol abuse in youth, little research has
yielded significant results regarding the long-term neurobiological
consequences of binge drinking at such a young age. Earlier in the semester,
Dr. Magdalena Szymanska from the Department of Physiology at Loyola University
Chicago’s Stritch School of Medicine presented her research on the effects of
excessive alcohol consumption in adolescents, namely how this consumption
affects the responsiveness of the hypothalamo-pituitary-adrenal (HPA) axis
which plays a role in regulating blood hormone levels.
For her research, Dr. Szymanska used
a rodent model to simulate adolescent binge drinking. The experimental rats
were treated with volumes of alcohol with the same duration and frequency that
would qualify as binge-drinking in adolescents. Control rats were treated with
the same duration and frequency but with saline treatments instead. These
treatments were given during puberty and then the rats were given a separate
treatment of alcohol or saline during adulthood. In order to measure the
effects of the alcohol consumption on the HPA axis, levels of hormones such as
corticotrophin-releasing hormone (CRH), arginine vasopressin (AVP), and
corticosterone (CORT) were measured before and after treatment. They
essentially found that binge-pattern alcohol consumption during adolescence
resulted in dysregulation of the HPA axis which can have significant
implications on the adult stress response. Disruption of the stress response can
result in mood disorders amongst other conditions in adolescents that can
easily be avoided if adolescents are hindered from such extreme levels of
alcohol consumption.
Another condition that is of great
concern for adolescents is attention deficit hyperactivity disorder (ADHD).
Unlike alcohol consumption in adolescents, numerous studies have been conducted
to find an association between various adolescent behaviors such as playing video
games and ADHD diagnosis. Stimulant medications such as Adderall and Ritalin
are often prescribed to treat adolescents with this condition. Despite these
readily available treatment options, parents are often hesitant about these
prescriptions because they do not want their children to develop a dependency
on pharmaceuticals at such a young age. Interestingly, one article published
earlier this year in The New York Times
mentioned a study that was done to see if there was a relationship between this
type of stimulant drug use to treat ADHD and later drug and alcohol abuse.
According to the article, parents’ fears about their children taking these
prescription medications were often eased by physicians and pharmaceutical
companies citing previous studies that claimed that stimulant medications such
as Adderall and Ritalin reduce the risk of these adolescents engaging in other
substance abuse later in life. However, the study cited by The New York Times article disproved this finding and actually
found that there is no relationship between stimulant medication use in adolescents
and subsequent substance abuse. Thus, these prescription medications do not
increase or decrease adolescent susceptibility to binge-drinking behavior yet
more and more adolescents continue to be diagnosed—and often misdiagnosed—with ADHD
and prescribed these medications as though they were both treating ADHD and
preventing possible alcoholism in the future. If anything, it seems to me that
these prescriptions are being used as an unconventional marketing strategy for
the prevention of drug and alcohol abuse in young people. Perhaps a more
effective and less dangerous prevention strategy would be to continue
encouraging the work of researchers such as Dr. Szymanska in their pursuit of
knowledge regarding the long-term neurobiological and developmental
consequences of alcohol consumption in the younger members of society. Further
knowledge of this sort can lead to further education of these adolescents so
they can have a stronger understanding of how their decisions to drink might
have lasting effects on their growth and development. This will then hopefully
encourage them to make better, well-informed decisions regarding their health
and reduce such harmful behaviors in our youth to allow for a brighter future.
Works Cited:
Przybycien-Szymanska, Magdalena, Natasha Mott,
Caitlin Paul, Roberta Gillespie, and Toni Pak. "Binge-Pattern Alcohol
Exposure during Puberty Induces Long-Term Changes in HPA Axis Reactivity." Plos
One. 6.4 (2011): 1-7. Web. 13 Dec. 2013.
Schwarz, Alan. "No Link Seen Between Child
Stimulant Use and Later Drug Abuse." New York Times 29 05 2013, n. pag. Web. 13 Dec.
2013. <http://www.nytimes.com/2013/05/30/health/no-impact-found-for-stimulants-on-later-drug-abuse.html?_r=0>.
"Youth Online: High School YRBS." .
Centers for Disease Control and Prevention. Web. 13 Dec 2013. <http: / / apps.nccd.cdc.gov
/ youthonline / App / Results.aspx?TT=&OUT=&SID=HS&QID=H43&LID=&YID=&LID2=&YID2=&COL=&ROW1=&ROW2=&HT=&LCT=&FS=&FR=&FG=&FSL=&FRL=&FGL=&PV=&TST=&C1=&C2=&QP=G&DP=&VA=CI&CS=Y&SYID=&EYID=&SC=&SO=>.
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